Deuteronomy 2:4
2:4 Instruct these people as follows: ‘You are about to cross the border of your relatives the descendants of Esau, who inhabit Seir. They will be afraid of you, so watch yourselves carefully.
Deuteronomy 2:22
2:22 This is exactly what he did for the descendants of Esau who lived in Seir when he destroyed the Horites before them so that they could dispossess them and settle in their area to this very day.