Isaiah 7:13

7:13 So Isaiah replied, “Pay attention, family of David. Do you consider it too insignificant to try the patience of men? Is that why you are also trying the patience of my God?

Isaiah 16:14

16:14 Now the Lord makes this announcement: “Within exactly three years Moab’s splendor will disappear, along with all her many people; there will be just a few, insignificant survivors left.”

Isaiah 53:3

53:3 He was despised and rejected by people,

one who experienced pain and was acquainted with illness;

people hid their faces from him;

he was despised, and we considered him insignificant.