Genesis 15:2

15:2 But Abram said, “O sovereign Lord, what will you give me since I continue to be childless, and my heir is Eliezer of Damascus?”

Genesis 25:21

25:21 Isaac prayed to the Lord on behalf of his wife because she was childless. The Lord answered his prayer, and his wife Rebekah became pregnant.

Genesis 42:36

42:36 Their father Jacob said to them, “You are making me childless! Joseph is gone. Simeon is gone. And now you want to take Benjamin! Everything is against me.”