Ephesians 4:18
4:18 They are darkened in their understanding, being alienated from the life of God because of the ignorance that is in them due to the hardness of their hearts.
Ephesians 2:12
2:12 that you were at that time without the Messiah, alienated from the citizenship of Israel and strangers to the covenants of promise, having no hope and without God in the world.