badness, hurtfulness, virulence, evil doer, bane, plague spot, evil star, ill wind, hoodoo, Jonah, snake in the grass, skeleton in the closet, amari aliquid, thorn in the side, malignity, malevolence, tender mercies, ill-treatment, annoyance, molestation, abuse, oppression, persecution, outrage, misusage, injury, knockout drops, badness, peccancy, abomination, painfulness, pestilence, guilt, depravity, hurtful, harmful, scathful, baneful, baleful, injurious, deleterious, detrimental, noxious, pernicious, mischievous, full of mischief, mischief-making, malefic, malignant, nocuous, noisome, prejudicial, disserviceable, disadvantageous, wide-wasting, unlucky, sinister, obnoxious, untoward, disastrous, oppressive, burdensome, onerous
, malign, corrupting &c (corrupt), virulent, venomous, envenomed, corrosive, poisonous, deadly, destructive, inauspicious, bad, ill, arrant, as bad as bad can be, dreadful, horrid, horrible, dire, rank, peccant, foul, fulsome, rotten, rotten at the core, vile, base, villainous, mean, injured, deteriorated, unsatisfactory, exceptionable indifferent, below par, illcontrived, ill-conditioned, wretched, sad, grievous, deplorable, lamentable, pitiful, pitiable, woeful, evil, wrong, depraved, shocking, reprehensible, hateful, hateful as a toad, abominable, detestable, execrable, cursed, accursed, confounded, damned, damnable, infernal, diabolic, unadvisable, unprofitable, incompetent, irremediable, badly, wrong, ill, to one's cost, where the shoe pinches, bad is the best: the worst come to the worst, herba mala presto cresco, wrongs unredressed or insults unavenged.
difficulty, hardness, impracticability, tough work, hard work, uphill work, hard task, Herculean task, Augean task, task of Sisyphus, Sisyphean labor, tough job, teaser, rasper, dead lift, dilemma, embarrassment, deadlock, perplexity, intricacy, entanglement, complexity, cross fire, awkwardness, delicacy, ticklish card to play, knot, Gordian knot, dignus vindice nodus, net, meshes, maze, coil, crooked path, involvement, nice point, delicate point, subtle point, knotty point, vexed question, vexata quaestio, poser, puzzle, paradox, hard nut to crack, nut to crack, bone to pick, crux, pons asinorum, where the shoe pinches, nonplus, quandary, strait, pass, pinch, pretty pass, stress, brunt, critical situation, crisis, trial, rub, emergency, exigency, scramble, scrape, hobble, slough, quagmire, hot water, hornet's nest, sea of troubles, peck of troubles, pretty kettle of fish, pickle, stew, imbroglio, mess, ado, false position, set fast, stand, standstill, deadlock, dead set, fix, horns of a dilemma, cul de sac, hitch, stumbling block, crab, curmudgeon, difficult, not easy, hard, tough, troublesome, toilsome, irksome, operose, laborious, onerous
, arduous, Herculean, formidable, sooner said than done, more easily said than done, easier said than done, difficult to deal with, hard to deal with, ill-conditioned, crabbed, crabby, not to be handled with kid gloves, not made with rose water, awkward, unwieldy, unmanageable, intractable, stubborn, perverse, refractory, plaguy, trying, thorny, rugged, knotted, knotty, invious, pathless, trackless, labyrinthine, intricate, complicated, impracticable, not feasible, desperate, embarrassing, perplexing, delicate, ticklish, critical, beset with difficulties, full of difficulties, surrounded by difficulties, entangled by difficulties, encompassed with difficulties, under a difficulty, in a box, in difficulty, in hot water, in the suds, in a cleft stick, in a fix, in the wrong box, in a scrape, in deep water, in a fine pickle, in extremis, between two stools, between Scylla and Charybdis, surrounded by shoals, surrounded by breakers, surrounded by quicksands, at cross purposes, not out of the wood, reduced to straits, hard pressed, sorely pressed, run hard, pinched, put to it, straitened, hard up, hard put to it, hard set, put to one's shifts, puzzled, at a loss, at the end of one's tether, at the end of one's rope, at one's wit's end, at a nonplus, at a standstill, graveled, nonplused, nonplussed, stranded, aground, stuck fast, set fast, up a tree, at bay, aux abois, driven into a corner, driven from pillar to post, driven to extremity, driven to one's wit's end, driven to the wall, au bout de son Latin, out of one's depth, thrown out, accomplished with difficulty, hard-fought, hard-earned, with difficulty, with much ado, barely, hardly, uphill, against the stream, against the grain, d rebours, invita Minerva, in the teeth of, at a pinch, upon a pinch, at long odds, against long odds, ay there's the rub, hic labor hoc opus, things are come to a pretty pass, ab inconvenienti, ad astra per aspera, acun chemin de fleurs ne conduit a la gloire.
hindrance, prevention, preclusion, obstruction, stoppage, embolus, embolism, infarct, interruption, interception, interclusion, hindrance, impedition, retardment, retardation, embarrassment, oppilation, coarctation, stricture, restriction, restraint, inhibition, blockade, interference, interposition, obtrusion, discouragement, discountenance, impediment, let, obstacle, obstruction, knot, knag, check, hitch, contretemps, screw loose, grit in the oil, bar, stile, barrier, turnstile, turnpike, gate, portcullis, beaver dam, trocha, barricade, wall, dead wall, sea wall, levee breakwater, groyne, bulkhead, block, buffer, stopper, boom, dam, weir, burrock, drawback, objection, stumbling-block, stumbling-stone, lion in the path, snag, snags and sawyers, encumbrance, incumbrance, clog, skid, shoe, spoke, drag, drag chain, drag weight, stay, stop, preventive, prophylactic, load, burden, fardel, onus, millstone round one's neck, impedimenta, dead weight, lumber, pack, nightmare, Ephialtes, incubus, old man of the sea, remora, difficulty, insuperable, obstacle, estoppel, ill wind, head wind, trammel, tether, hold back, counterpoise, damper, wet blanket, hinderer, marplot, killjoy, party pooper, party crasher, interloper, trail of a red herring, opponent, hindering, obstructive, obstruent, impeditive, impedient, intercipient, prophylactic, impedimentary, in the way of, unfavorable, onerous
, burdensome, cumbrous, cumbersome, obtrusive, hindered, windbound, waterlogged, heavy laden, hard pressed, unassisted &c (assist), single-handed, alone, deserted, occurrent nubes.
painfulness, trouble, care, trial, affliction, infliction, blow, stroke, burden, load, curse, bitter pill, bitter draught, waters of bitterness, annoyance, grievance, nuisance, vexation, mortification, sickener, bore, bother, pother, hot water, sea of troubles, hornet's nest, plague, pest, cancer, ulcer, sting, thorn, canker, scorpion, dagger, scourge, carking care, canker worm of care, mishap, misfortune, desagrement, esclandre, rub, source of irritation, source of annoyance, wound, open sore, sore subject, skeleton in the closet, thorn in the flesh, thorn in one's side, where the shoe pinches, gall and wormwood, sorry sight, heavy news, provocation, affront, head and front of one's offending, infestation, molestation, malignity, causing pain, hurting, hurtful, painful, dolorific, dolorous, unpleasant, unpleasing, displeasing, disagreeable, unpalatable, bitter, distasteful, uninviting, unwelcome, undesirable, undesired, obnoxious, unacceptable, unpopular, thankless, unsatisfactory, untoward, unlucky, uncomfortable, distressing, afflicting, afflictive, joyless, cheerless, comfortless, dismal, disheartening, depressing, depressive, dreary, melancholy, grievous, piteous, woeful, rueful, mournful, deplorable, pitiable, lamentable, sad, affecting, touching, pathetic, irritating, provoking, stinging, annoying, aggravating, mortifying, galling, unaccommodating, invidious, vexatious, troublesome, tiresome, irksome, wearisome, plaguing, plaguy, awkward, importunate, teasing, pestering, bothering, harassing, worrying, tormenting, carking, intolerable, insufferable, insupportable, unbearable, unendurable, past bearing, not to be borne, not to be endured, more than flesh and blood can bear, enough to drive one mad, enough to provoke a saint, enough to make a parson swear, enough to gag a maggot, shocking, terrific, grim, appalling, crushing, dreadful, fearful, frightful, thrilling, tremendous, dire, heart-breaking, heart-rending, heart-wounding, heart-corroding, heart-sickening, harrowing, rending, odious, hateful, execrable, repulsive, repellent, abhorrent, horrid, horrible, horrific, horrifying, offensive, nauseous, nauseating, disgusting, sickening, revolting, nasty, loathsome, loathful, fulsome, vile, hideous, sharp, acute, sore, severe, grave, hard, harsh, cruel, biting, caustic, cutting, corroding, consuming, racking, excruciating, searching, grinding, grating, agonizing, envenomed, catheretic, pyrotic, ruinous, disastrous, calamitous, tragical, desolating, withering, burdensome, onerous
, oppressive, cumbrous, cumbersome, painfully, with pain, deuced, Int, hinc illae lachrymae!, surgit amari aliquid, the place being too hot to hold one, the iron entering into the soul, he jests at scars that never felt a wound, I must be cruel only to be kind, what deep wounds ever closed without a scar?.